About the "right tool for the job" point made above, of course there's something in that. But it's not quite like picking the right wrench for particular nuts and bolts.
Some people may do many different kinds of writing jobs, from quick note taking (even shorthand) to painstakingly executed calligraphy in different styles, to drawing. I'll admit to breaking out the italic nibs sometimes, usually for birthday or Christmas cards. Almost all of the jobs that my pens have to do, though, would come under general writing. I may pause to admire the look of a particular ink from time to time, or note that my handwriting appears particularly neat yet elegant that day (not an opinion likely to be shared by many) but most of the time I'm concentrated on what I'm writing. I may be over-interpreting what the OP meant, but I took the question to be, what do you prefer for the kind of writing you do most? When it's a matter of getting words down on paper without being distracted by the tools you're using, what sort of pen works best for you (and has your preference changed)?
If that's the question, I think it's quite possible to have one favorite type of nib. You may still like to change, occasionally, but that's more from a taste for variety than it is of one nib being more suitable than another.
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